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Prevalence of Single Nucleotide Polymorphisms in the Plasmodium falciparum Multidrug Resistance Gene (Pfmdr-1) in Korogwe District in Tanzania Before and After Introduction of Artemisinin-Based Combination Therapy

Tanzania implemented artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in November of 2006 because of resistance to sulfadoxine-pyrimethamine. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance, which i...

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Detalhes bibliográficos
Main Authors: Thomsen, Thomas T., Ishengoma, Deus S., Mmbando, Bruno P., Lusingu, John P., Vestergaard, Lasse S., Theander, Thor G., Lemnge, Martha M., Bygbjerg, Ib C., Alifrangis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225174/
https://ncbi.nlm.nih.gov/pubmed/22144430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2011.11-0071
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