Differences in Human Antibody Reactivity to Plasmodium falciparum Variant Surface Antigens Are Dependent on Age and Malaria Transmission Intensity in Northeastern Tanzania

Plasmodium falciparum variant surface antigens (VSA) are involved in the pathogenesis of malaria. Immunoglobulin G (IgG) with specificity for VSA (anti-VSA IgG) is therefore considered important for acquired immunity. To better understand the nature and dynamics of variant-specific IgG responses at...

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Detalhes bibliográficos
Main Authors: Vestergaard, Lasse S., Lusingu, John P., Nielsen, Morten A., Mmbando, Bruno P., Dodoo, Daniel, Akanmori, Bartholomew D., Alifrangis, Michael, Bygbjerg, Ib C., Lemnge, Martha M., Staalsoe, Trine, Hviid, Lars, Theander, Thor G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423063/
https://ncbi.nlm.nih.gov/pubmed/18250179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01401-06
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