HMGB1 contributes to allergen-induced airway remodeling in a murine model of chronic asthma by modulating airway inflammation and activating lung fibroblasts

The pro-inflammation factor high-mobility group box protein 1 (HMGB1) has been implicated in the pathogenesis of asthma. In this study, we used a murine model of chronic asthma to evaluate the effects of HMGB1 on airway remodeling. Female BALB/c mice were randomly divided into four groups: control,...

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Publicat a:Cell Mol Immunol
Autors principals: Hou, Changchun, Kong, Jinliang, Liang, Yue, Huang, Hong, Wen, Hanchun, Zheng, Xiaowen, Wu, Lihong, Chen, Yiqiang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496537/
https://ncbi.nlm.nih.gov/pubmed/25152078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.60
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