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Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma

1. To clarify the involvement of Th2 responses in the development of allergen-induced airway remodelling, we investigated the effect of anti-CD4 monoclonal antibody (mAb) and anti-CD8 mAb, and the responses of IL-4 gene-knockout (KO) mice in a murine model of allergic asthma. 2. Mice were immunized...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Komai, Masato, Tanaka, Hiroyuki, Masuda, Taisei, Nagao, Koichi, Ishizaki, Masayuki, Sawada, Masatsugu, Nagai, Hiroichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573716/
https://ncbi.nlm.nih.gov/pubmed/12642393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705105
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