Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach

Retinoid X receptor (RXR) and Histone deacetylase (HDAC) are considered important targets for cancer therapy due to their crucial roles in genetic or epigenetic regulations of cancer development and progression. Here, we evaluated the potential of dual targeting of RXR and HDAC using DW22 as a novel...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Lihui, Chen, Guoliang, Chen, Kang, Ren, Yong, Li, Huahuan, Jiang, Xiaorui, Jia, Lina, Fu, Shiyuan, Li, Yi, Liu, Xinwei, Wang, Shuang, Yang, Jingyu, Wu, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496394/
https://ncbi.nlm.nih.gov/pubmed/25762635
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