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Negative regulation of mitosis in fission yeast by catalytically inactive pyp1 and pyp2 mutants.

The Schizosaccharomyces pombe genes pyp1+ and pyp2+ encode protein tyrosine phosphatases (PTPases) that act as negative regulators of mitosis upstream of the wee1+/mik1+ pathway. Here we provide evidence that pyp1+ and pyp2+ function independently of cdr1+(nim1+) in the inhibition of mitosis and tha...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Hannig, G, Ottilie, S, Erikson, R L
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1994
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937842/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.10084
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