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Negative regulation of mitosis in fission yeast by catalytically inactive pyp1 and pyp2 mutants.

The Schizosaccharomyces pombe genes pyp1+ and pyp2+ encode protein tyrosine phosphatases (PTPases) that act as negative regulators of mitosis upstream of the wee1+/mik1+ pathway. Here we provide evidence that pyp1+ and pyp2+ function independently of cdr1+(nim1+) in the inhibition of mitosis and tha...

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Main Authors: Hannig, G, Ottilie, S, Erikson, R L
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC44962/
https://ncbi.nlm.nih.gov/pubmed/7937842
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