Healthy human salivary glands contain a DHEA-sulphate processing intracrine machinery, which is deranged in primary Sjögren’s syndrome

Sjögren’s syndrome (SS) patients have low salivary dehydroepiandrosterone (DHEA) and androgen biomarker levels, but high salivary oestrogen levels. The hypothesis was that the healthy glands contain DHEA-sulphate processing intracrine machinery; the local androgen/oestrogen imbalance suggests that t...

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Udgivet i:J Cell Mol Med
Main Authors: Spaan, Michelle, Porola, Pauliina, Laine, Mikael, Rozman, Blaz, Azuma, Masayuki, Konttinen, Yrjö T
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496140/
https://ncbi.nlm.nih.gov/pubmed/19298523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00727.x
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