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In rats, oral oleoyl-DHEA is rapidly hydrolysed and converted to DHEA-sulphate

BACKGROUND: Dehydroepiandrosterone (DHEA) released by adrenal glands may be converted to androgens and estrogens mainly in the gonadal, adipose, mammary, hepatic and nervous tissue. DHEA is also a key neurosteroid and has antiglucocorticoid activity. DHEA has been used for the treatment of a number...

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Detalhes bibliográficos
Main Authors: Serrano, Marta, Grasa, Maria del Mar, Fernández-López, José Antonio, Alemany, Marià
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831771/
https://ncbi.nlm.nih.gov/pubmed/17346356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-7-4
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