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Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth

Taxol is a powerful chemotherapeutic agent that binds to microtubules to prevent tumour cell division. However, a traditional high dose of taxol may also induce apoptosis in normal cells. The anti-apoptotic molecule Bcl-2 is up-regulated in tumour cells to prevent apoptosis. We designed this study t...

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Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: George, Joseph, Banik, Naren L, Ray, Swapan K
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496127/
https://ncbi.nlm.nih.gov/pubmed/19473291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00539.x
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