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Genistein Induces Receptor and Mitochondrial Pathways and Increases Apoptosis during Bcl-2 Knockdown in Human Malignant Neuroblastoma SK-N-DZ Cells

The potent anti-apoptotic molecule Bcl-2 is markedly upregulated in majority of cancers including neuroblastoma. Genistein is an isoflavone with anti-tumor properties. The present study was aimed to elucidate the molecular mechanism of genistein induced apoptosis and also to examine the effect of ge...

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Detalhes bibliográficos
Main Authors: George, Joseph, Banik, Naren L., Ray, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118305/
https://ncbi.nlm.nih.gov/pubmed/19813266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22244
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