Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling

Geraniol exerts several direct pharmacological effects on tumor cells and, thus, has been suggested as a promising anti-cancer compound. Because vascularization is a major precondition for tumor growth, we analyzed in this study the anti-angiogenic action of geraniol. In vitro, geraniol reduced the...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wittig, Christine, Scheuer, Claudia, Parakenings, Julia, Menger, Michael D., Laschke, Matthias W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496091/
https://ncbi.nlm.nih.gov/pubmed/26154255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131946
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