MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease

Recent studies have found that extracellular vesicles (EVs) play an important role in normal and disease processes. In the present study, we isolated and characterized EVs from the brains of rhesus macaques, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CN...

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Vydáno v:PLoS Pathog
Hlavní autoři: Yelamanchili, Sowmya V., Lamberty, Benjamin G., Rennard, Deborah A., Morsey, Brenda M., Hochfelder, Colleen G., Meays, Brittney M., Levy, Efrat, Fox, Howard S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496044/
https://ncbi.nlm.nih.gov/pubmed/26154133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005032
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