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MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease

Recent studies have found that extracellular vesicles (EVs) play an important role in normal and disease processes. In the present study, we isolated and characterized EVs from the brains of rhesus macaques, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CN...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Yelamanchili, Sowmya V., Lamberty, Benjamin G., Rennard, Deborah A., Morsey, Brenda M., Hochfelder, Colleen G., Meays, Brittney M., Levy, Efrat, Fox, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496044/
https://ncbi.nlm.nih.gov/pubmed/26154133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005032
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