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Unraveling the pivotal role of ALIX in MVB sorting and silencing of activated EGFR

ESCRT-III mediated membrane invagination and scission is a critical step in MVB sorting of ubiquitinated membrane receptors and generally thought to be required for degradation of these receptors in lysosomes. The adaptor protein ALIX is critically involved in multiple ESCRT-III-mediated membrane re...

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Bibliographic Details
Published in:Biochem J
Main Authors: Sun, Sheng, Zhou, Xi, Zhang, Wei, Gallick, Gary E., Kuang, Jian
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495973/
https://ncbi.nlm.nih.gov/pubmed/25510652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141156
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