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Freeze-thaw cycles as drivers of complex ribozyme assembly

The emergence of an RNA catalyst capable of self-replication is considered a key transition in the origin of life. However, how such replicase ribozymes emerged from the pools of short RNA oligomers arising from prebiotic chemistry and non-enzymatic replication is unclear. Here we show that RNA poly...

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Détails bibliographiques
Publié dans:Nat Chem
Auteurs principaux: Mutschler, Hannes, Wochner, Aniela, Holliger, Philipp
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495579/
https://ncbi.nlm.nih.gov/pubmed/25991529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2251
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