Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells

Mutant p53 impacts the expression of numerous genes at the level of transcription to mediate oncogenesis. We identified vascular endothelial growth factor receptor 2 (VEGFR2), the primary functional VEGF receptor that mediates endothelial cell vascularization, as a mutant p53 transcriptional target...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Pfister, Neil T., Fomin, Vitalay, Regunath, Kausik, Zhou, Jeffrey Y., Zhou, Wen, Silwal-Pandit, Laxmi, Freed-Pastor, William A., Laptenko, Oleg, Neo, Suat Peng, Bargonetti, Jill, Hoque, Mainul, Tian, Bin, Gunaratne, Jayantha, Engebraaten, Olav, Manley, James L., Børresen-Dale, Anne-Lise, Neilsen, Paul M., Prives, Carol
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495400/
https://ncbi.nlm.nih.gov/pubmed/26080815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263202.115
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires