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Intestinal apical polarity mediates regulation of TORC1 by glucosylceramide in C. elegans

TORC1 (target of rapamycin complex 1) plays a central role in regulating growth, development, and behavior in response to nutrient cues. We previously showed that leucine-derived monomethyl branched-chain fatty acids (mmBCFAs) and derived glucosylceramide promote intestinal TORC1 activity for post-e...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Zhu, Huanhu, Sewell, Aileen K., Han, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495394/
https://ncbi.nlm.nih.gov/pubmed/26109047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263483.115
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