Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice

Intense effort has been devoted to understanding predisposition to chronic systemic inflammation as this contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) in mice (KODMAC) is sufficient to induce insulin resistance by promoting M2 macroph...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Oh, Jisu, Riek, Amy E., Darwech, Isra, Funai, Katsuhiko, Shao, JianSu, Chin, Kathleen, Sierra, Oscar L., Carmeliet, Geert, Ostlund, Richard E., Bernal-Mizrachi, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495012/
https://ncbi.nlm.nih.gov/pubmed/25801026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.043
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker