Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition

Tyrosine kinase inhibitors (TKIs) are now the mainstay of treatment in many types of cancer. However, their benefit is frequently short-lived, mandating the search for safe potentiation strategies. Cycles of fasting enhance the activity of chemo-radiotherapy in preclinical cancer models and dietary...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Caffa, Irene, D'Agostino, Vito, Damonte, Patrizia, Soncini, Debora, Cea, Michele, Monacelli, Fiammetta, Odetti, Patrizio, Ballestrero, Alberto, Provenzani, Alessandro, Longo, Valter D., Nencioni, Alessio
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Priority Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494907/
https://ncbi.nlm.nih.gov/pubmed/25909220
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