Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated individuals

BACKGROUND: Peanut oral immunotherapy (PNOIT) induces persistent tolerance to peanut in a subset of patients and induces specific antibodies which may play a role in clinical protection. The contribution of induced antibody clones to clinical tolerance in PNOIT is unknown, however. OBJECTIVE: We hyp...

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Udgivet i:J Allergy Clin Immunol
Main Authors: Patil, Sarita U., Ogunniyi, Adebola O., Calatroni, Agustin, Tadigotla, Vasisht R., Ruiter, Bert, Ma, Alex, Moon, James, Love, J.Christopher, Shreffler, Wayne G.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494892/
https://ncbi.nlm.nih.gov/pubmed/25985925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.03.026
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