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Liver mitochondrial cytochrome P450 CYP27 and recombinant-expressed human CYP27 catalyze 1 alpha-hydroxylation of 25-hydroxyvitamin D3.

A cytochrome P450 catalyzing 1 alpha-hydroxylation of 25-hydroxyvitamin D3 was purified from pig liver mitochondria. It also catalyzed 27-hydroxylation of 25-hydroxyvitamin D3 and 25-hydroxylation of vitamin D3. The ratio between the 1 alpha-, 27-, and 25-hydroxylase activities remained essentially...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Axén, E, Postlind, H, Sjöberg, H, Wikvall, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44948/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.10014
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