Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket
4-Hydroxyisophorone (4HIP) is an oxygenated intermediate derived from isophorone, serving as an important flavor and fragrance and chiral synthon of pharmaceutical drugs. In this study, a newly identified P450CYP107J3 from Bacillus cereus was found to prefer 4-hydroxylation of isophorone (80% regios...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
KeAi Communications Co. Ltd.
2026-04-01
|
| シリーズ: | Green Synthesis and Catalysis |
| 主題: | |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S2666554924000620 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|