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Antimalarial Activity of Natural and Synthetic Prodiginines
Prodiginines are a family of linear and cyclic oligopyrrole red-pigmented compounds. Herein we describe the in vitro antimalarial activity of 4 natural (IC(50) = 1.7-8.0 nM) and 3 sets of synthetic prodiginines against Plasmodium falciparum. Set 1 compounds replaced the terminal non-alkylated pyrrol...
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| Veröffentlicht in: | J Med Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494750/ https://ncbi.nlm.nih.gov/pubmed/21736388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200543y |
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