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Two novel Brugada syndrome-associated mutations increase K(V)4.3 membrane expression and function
The human cardiac fast transient outward K(+) channel is composed of the K(V)4.3 α subunit encoded by KCND3 and the K(+) channel-interacting protein 2 (KChIP2) β subunit, and determines the early repolarization of the action potential (AP). Two human mutations (G600R and L450F) in K(V)4.3 are associ...
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| Gepubliceerd in: | Int J Mol Med |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
D.A. Spandidos
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494594/ https://ncbi.nlm.nih.gov/pubmed/26016905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2223 |
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