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Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP

The potent adjuvant activity of the novel adjuvant, poly[di(sodiumcarboxylatoethylphenoxy)phosphazene] (PCEP), with various antigens has been reported previously. However, very little is known about its mechanisms of action. We have recently reported that intramuscular injection of PCEP induces NLRP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Awate, Sunita, Eng, Nelson F., Gerdts, Volker, Babiuk, Lorne A., Mutwiri, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494223/
https://ncbi.nlm.nih.gov/pubmed/26344742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines2030500
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