Quaternary structure defines a large class of amyloid-β oligomers neutralized by sequestration

The accumulation of amyloid-β (Aβ) as amyloid fibrils and toxic oligomers is an important step in the development of Alzheimer's disease (AD). However, there are numerous potentially toxic oligomers and little is known about their neurological effects when generated in the living brain. Here, w...

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Publicado en:Cell Rep
Autores principales: Liu, Peng, Reed, Miranda N., Kotilinek, Linda A., Grant, Marianne K.O., Forster, Colleen L., Qiang, Wei, Shapiro, Samantha L., Reichl, John H., Chiang, Angie C.A., Jankowsky, Joanna L., Wilmot, Carrie M., Cleary, James P., Zahs, Kathleen R., Ashe, Karen H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494129/
https://ncbi.nlm.nih.gov/pubmed/26051935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.021
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