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Correlation of Specific Amyloid-β Oligomers With Tau in Cerebrospinal Fluid From Cognitively Normal Older Adults

OBJECTIVE: To investigate two specific amyloid-β (Aβ) oligomers, Aβ trimers and Aβ*56, in human cerebrospinal fluid (CSF), evaluate the effects of aging and Alzheimer's disease (AD), and obtain support for the hypothesis that they may be pathogenic by determining their relationships to CSF tau....

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Detalhes bibliográficos
Main Authors: Handoko, Maureen, Grant, Marianne, Kuskowski, Michael, Zahs, Kathleen R., Wallin, Anders, Blennow, Kaj, Ashe, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725752/
https://ncbi.nlm.nih.gov/pubmed/23479202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.48
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