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Is selection relevant in the evolutionary emergence of drug resistance?
The emergence of drug resistant pathogens is often considered a canonical case of evolution by ‘natural’ selection. Here we argue that the strength of selection can be a poor predictor of the rate of resistance emergence. It is possible for a resistant strain to be under negative selection and still...
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| Publicado no: | Trends Microbiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494118/ https://ncbi.nlm.nih.gov/pubmed/25680587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2015.01.005 |
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