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Relevance of Undetectably Rare Resistant Malaria Parasites in Treatment Failure: Experimental Evidence from Plasmodium chabaudi
Resistant malaria parasites are frequently found in mixed infections with drug-sensitive parasites. Particularly early in the evolutionary process, the frequency of these resistant mutants can be extremely low and below the level of molecular detection. We tested whether the rarity of resistance in...
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| Publicado no: | Am J Trop Med Hyg |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Tropical Medicine and Hygiene
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458828/ https://ncbi.nlm.nih.gov/pubmed/25940195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0036 |
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