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Relevance of Undetectably Rare Resistant Malaria Parasites in Treatment Failure: Experimental Evidence from Plasmodium chabaudi
Resistant malaria parasites are frequently found in mixed infections with drug-sensitive parasites. Particularly early in the evolutionary process, the frequency of these resistant mutants can be extremely low and below the level of molecular detection. We tested whether the rarity of resistance in...
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| Publicado en: | Am J Trop Med Hyg |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society of Tropical Medicine and Hygiene
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458828/ https://ncbi.nlm.nih.gov/pubmed/25940195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0036 |
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