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Transposable Elements and DNA Methylation Create in Embryonic Stem Cells Human-Specific Regulatory Sequences Associated with Distal Enhancers and Noncoding RNAs
Despite significant progress in the structural and functional characterization of the human genome, understanding of the mechanisms underlying the genetic basis of human phenotypic uniqueness remains limited. Here, I report that transposable element-derived sequences, most notably LTR7/HERV-H, LTR5_...
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| Publicado en: | Genome Biol Evol |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494056/ https://ncbi.nlm.nih.gov/pubmed/25956794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv081 |
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