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Transposable Elements and DNA Methylation Create in Embryonic Stem Cells Human-Specific Regulatory Sequences Associated with Distal Enhancers and Noncoding RNAs

Despite significant progress in the structural and functional characterization of the human genome, understanding of the mechanisms underlying the genetic basis of human phenotypic uniqueness remains limited. Here, I report that transposable element-derived sequences, most notably LTR7/HERV-H, LTR5_...

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Bibliografske podrobnosti
izdano v:Genome Biol Evol
Glavni avtor: Glinsky, Gennadi V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494056/
https://ncbi.nlm.nih.gov/pubmed/25956794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv081
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