Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

Various strategies have been published enabling cardiomyocyte differentiation of human induced pluripotent stem (iPS) cells. However the complex nature of signaling pathways involved as well as line-to-line variability compromises the application of a particular protocol to robustly obtain cardiomyo...

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Vydáno v:Stem Cell Rev
Hlavní autoři: Kadari, Asifiqbal, Mekala, SubbaRao, Wagner, Nicole, Malan, Daniela, Köth, Jessica, Doll, Katharina, Stappert, Laura, Eckert, Daniela, Peitz, Michael, Matthes, Jan, Sasse, Philipp, Herzig, Stefan, Brüstle, Oliver, Ergün, Süleyman, Edenhofer, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493626/
https://ncbi.nlm.nih.gov/pubmed/25392050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-014-9564-6
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