Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

Various strategies have been published enabling cardiomyocyte differentiation of human induced pluripotent stem (iPS) cells. However the complex nature of signaling pathways involved as well as line-to-line variability compromises the application of a particular protocol to robustly obtain cardiomyo...

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Veröffentlicht in:Stem Cell Rev
Hauptverfasser: Kadari, Asifiqbal, Mekala, SubbaRao, Wagner, Nicole, Malan, Daniela, Köth, Jessica, Doll, Katharina, Stappert, Laura, Eckert, Daniela, Peitz, Michael, Matthes, Jan, Sasse, Philipp, Herzig, Stefan, Brüstle, Oliver, Ergün, Süleyman, Edenhofer, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493626/
https://ncbi.nlm.nih.gov/pubmed/25392050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-014-9564-6
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