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Revealing Three Stages of DNA-Cisplatin Reaction by a Solid-State Nanopore
The dynamic structural behavior in DNA due to interaction with cisplatin is essential for the functionality of platinum-based anti-cancer drugs. Here we report a novel method to monitor the interaction progress in DNA-cisplatin reaction in real time with a solid-state nanopore. The interaction proce...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493569/ https://ncbi.nlm.nih.gov/pubmed/26148968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11868 |
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