Intravitreal TSG-6 suppresses laser-induced choroidal neovascularization by inhibiting CCR2(+) monocyte recruitment

Choroidal neovascularization (CNV) is the hallmark of wet age-related macular degeneration (AMD), one of the leading causes of blindness in the elderly. Although the pathogenesis of CNV is not clear, a number of studies show that ocular-infiltrating macrophages and inflammation play a critical role...

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Published in:Sci Rep
Main Authors: Jin Kim, Sang, Ju Lee, Hyun, Yun, Ji-Hyun, Hwa Ko, Jung, Choi, Da Ye, Youn Oh, Joo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493567/
https://ncbi.nlm.nih.gov/pubmed/26149224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11872
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