Intravitreal itraconazole inhibits laser-induced choroidal neovascularization in rats

Choroidal neovascularization (CNV) is a major cause of severe visual loss in patients with age-related macular degeneration (AMD). Recently, itraconazole has shown potent and dose-dependent inhibition of tumor-associated angiogenesis. We evaluated the anti-angiogenic effect of itraconazole in a rat...

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Pubblicato in:PLoS One
Autori principali: Bae, Jeong Hun, Hwang, Ah Reum, Kim, Chan Yun, Yu, Hyeong Gon, Koh, Hyoung Jun, Yang, Woo Ick, Chang, Hae Ran, Lee, Sung Chul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493406/
https://ncbi.nlm.nih.gov/pubmed/28666022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180482
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