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A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature. Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The mechanism of CSF entry into the LNs has been unclear. Here we report the surprising finding of a lymphatic vessel networ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Aspelund, Aleksanteri, Antila, Salli, Proulx, Steven T., Karlsen, Tine Veronica, Karaman, Sinem, Detmar, Michael, Wiig, Helge, Alitalo, Kari
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493418/
https://ncbi.nlm.nih.gov/pubmed/26077718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142290
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