Exploring Genetic Factors Involved in Huntington Disease Age of Onset: E2F2 as a New Potential Modifier Gene

Age of onset (AO) of Huntington disease (HD) is mainly determined by the length of the CAG repeat expansion (CAGexp) in exon 1 of the HTT gene. Additional genetic variation has been suggested to contribute to AO, although the mechanism by which it could affect AO is presently unknown. The aim of thi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Valcárcel-Ocete, Leire, Alkorta-Aranburu, Gorka, Iriondo, Mikel, Fullaondo, Asier, García-Barcina, María, Fernández-García, José Manuel, Lezcano-García, Elena, Losada-Domingo, José María, Ruiz-Ojeda, Javier, Álvarez de Arcaya, Amaia, Pérez-Ramos, José María, Roos, Raymund A. C., Nielsen, Jørgen E., Saft, Carsten, Zubiaga, Ana M., Aguirre, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493078/
https://ncbi.nlm.nih.gov/pubmed/26148071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131573
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados