Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment

BACKGROUND: The self-renewing ability of HSCs is fundamental for the maintenance of a pool of bone marrow precursors throughout the life of an individual. The genetic mechanisms underlying such a complex process are still poorly understood. RESULTS AND SIGNIFICANCE: Here, we show that constitutive i...

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Publicado en:PLoS One
Main Authors: Kauffman, Lauren, Balatti, Veronica, Cascione, Luciano, Fadda, Paolo, Racke, Frederick, Santhanam, Ramasamy, Costinean, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492741/
https://ncbi.nlm.nih.gov/pubmed/26147501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131981
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