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Cis-Suppression to Arrest Protein Aggregation in Mammalian Cells

Protein misfolding and aggregation are implicated in numerous human diseases and significantly lower production yield of proteins expressed in mammalian cells. Despite the importance of understanding and suppressing protein aggregation in mammalian cells, a protein design and selection strategy to m...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Gregoire, Simpson, Zhang, Shaojie, Costanzo, Joseph, Wilson, Kelly, Fernandez, Erik J., Kwon, Inchan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492694/
https://ncbi.nlm.nih.gov/pubmed/24114411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25119
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