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Cis-Suppression to Arrest Protein Aggregation in Mammalian Cells

Protein misfolding and aggregation are implicated in numerous human diseases and significantly lower production yield of proteins expressed in mammalian cells. Despite the importance of understanding and suppressing protein aggregation in mammalian cells, a protein design and selection strategy to m...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Biotechnol Bioeng
Hlavní autoři: Gregoire, Simpson, Zhang, Shaojie, Costanzo, Joseph, Wilson, Kelly, Fernandez, Erik J., Kwon, Inchan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492694/
https://ncbi.nlm.nih.gov/pubmed/24114411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25119
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