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Cis-Suppression to Arrest Protein Aggregation in Mammalian Cells

Protein misfolding and aggregation are implicated in numerous human diseases and significantly lower production yield of proteins expressed in mammalian cells. Despite the importance of understanding and suppressing protein aggregation in mammalian cells, a protein design and selection strategy to m...

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Bibliografiske detaljer
Udgivet i:Biotechnol Bioeng
Main Authors: Gregoire, Simpson, Zhang, Shaojie, Costanzo, Joseph, Wilson, Kelly, Fernandez, Erik J., Kwon, Inchan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492694/
https://ncbi.nlm.nih.gov/pubmed/24114411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25119
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