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A Safe, Blood-Brain Barrier Permeable Triphenylmethane Dye Inhibits Amyloid-β Neurotoxicity by Generating Nontoxic Aggregates
[Image: see text] Growing evidence suggests that on-pathway amyloid-β (Aβ) oligomers are primary neurotoxic species and have a direct correlation with the onset of Alzheimer’s disease (AD). One promising therapeutic strategy to block AD progression is to reduce the levels of these neurotoxic Aβ spec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369715/ https://ncbi.nlm.nih.gov/pubmed/22860159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200056g |
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