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The scaffold protein RACK1 mediates the RANKL-dependent activation of p38 MAPK in osteoclast precursors
The E3 ubiquitin ligase TRAF6 and the associated kinase TAK1 are key components of the signaling pathways that activate nuclear factor κB (NF-κB) and mitogen-activated protein kinases (MAPKs) in response to various stimuli. The cytokine RANKL (receptor activator of NF-κB ligand) is essential for the...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492518/ https://ncbi.nlm.nih.gov/pubmed/26038599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005867 |
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