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FOXO1 Mediates RANKL Induced Osteoclast Formation and Activity

We have previously shown that the transcription factor FOXO1 is elevated in conditions with high levels of bone resorption. To investigate the role of FOXO1 in the formation of osteoclasts we examined mice with lineage specific deletion of FOXO1 in osteoclast precursors and by knockdown of FOXO1 wit...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wang, Yu, Dong, Guangyu, Jeon, Hyeran Helen, Elazizi, Mohamad, La, Lan B., Hameedaldeen, Alhassan, Xiao, E, Tian, Chen, Alsadun, Sarah, Choi, Yongwon, Graves, Dana T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355282/
https://ncbi.nlm.nih.gov/pubmed/25694609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402211
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