FOXO1 deletion in keratinocytes improves diabetic wound healing through MMP9 regulation

Keratinocyte migration is a key aspect of re-epithelialization during wound healing. Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Chenying, Lim, Jason, Jeon, Hyeran Helen, Xu, Fanxing, Tian, Chen, Miao, Fang, Hameedaldeen, Alhassan, Graves, Dana T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585410/
https://ncbi.nlm.nih.gov/pubmed/28874756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10999-3
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