Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Snail family members regulate epithelial-to-mesenchymal transition (EMT) during invasion of intestinal tumours, but their role in normal intestinal homeostasis is unknown. Studies in breast and skin epithelia indicate that Snail proteins promote an undifferentiated state. Here, we demonstrate that c...

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Vydáno v:EMBO J
Hlavní autoři: Horvay, Katja, Jardé, Thierry, Casagranda, Franca, Perreau, Victoria M, Haigh, Katharina, Nefzger, Christian M, Akhtar, Reyhan, Gridley, Thomas, Berx, Geert, Haigh, Jody J, Barker, Nick, Polo, Jose M, Hime, Gary R, Abud, Helen E
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491994/
https://ncbi.nlm.nih.gov/pubmed/25759216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490881
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