Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Snail family members regulate epithelial-to-mesenchymal transition (EMT) during invasion of intestinal tumours, but their role in normal intestinal homeostasis is unknown. Studies in breast and skin epithelia indicate that Snail proteins promote an undifferentiated state. Here, we demonstrate that c...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Horvay, Katja, Jardé, Thierry, Casagranda, Franca, Perreau, Victoria M, Haigh, Katharina, Nefzger, Christian M, Akhtar, Reyhan, Gridley, Thomas, Berx, Geert, Haigh, Jody J, Barker, Nick, Polo, Jose M, Hime, Gary R, Abud, Helen E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491994/
https://ncbi.nlm.nih.gov/pubmed/25759216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490881
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