DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

BACKGROUND: Although the etiology of primary biliary cirrhosis (PBC) remains enigmatic, there are several pieces of data supporting the thesis that a strong genetic predisposition and environmental factors interact to produce a selective loss of tolerance. The striking female predominance of PBC has...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Lleo, Ana, Zhang, Weici, Zhao, Ming, Tan, Yixin, Bernuzzi, Francesca, Zhu, Bochen, Liu, Qian, Tan, Qiqun, Malinverno, Federica, Valenti, Luca, Jiang, Tingting, Tan, Lina, Liao, Wei, Coppel, Ross, Invernizzi, Pietro, Lu, Qianjin, Adams, David H., Gershwin, M. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491885/
https://ncbi.nlm.nih.gov/pubmed/26150899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0098-9
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