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Functional organization of the human 4D Nucleome

The 4D organization of the interphase nucleus, or the 4D Nucleome (4DN), reflects a dynamical interaction between 3D genome structure and function and its relationship to phenotype. We present initial analyses of the human 4DN, capturing genome-wide structure using chromosome conformation capture an...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chen, Haiming, Chen, Jie, Muir, Lindsey A., Ronquist, Scott, Meixner, Walter, Ljungman, Mats, Ried, Thomas, Smale, Stephen, Rajapakse, Indika
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491792/
https://ncbi.nlm.nih.gov/pubmed/26080430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505822112
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